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epi AGE

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How Old Are You?

The only number that matters is your biological DNA age

People age at different rates. Some “look” and “feel” older than their chronological age while others look younger than their chronological age.

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How Old Are You? ​ Why Is It Important?

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Our biological age is a better parameter of our health well being and life span than our chronological age.

DNA is the hardware, genetics is the operating system and DNA methylation and other epigenetic factors are the software that programs the genome.

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A paradigm shift in the search for biological agemarkers occurred with the discovery of the “epigenetic clock” by Horvath, which is based on the measurement of DNA methylation status at 500 strategic positions in DNA.

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Studies suggest that accelerated “epigenetic clock” might be associated with increased risk for several age-related chronic diseases such as cardiovascular disease and cancer at later age. This is however still an open field and more studies are needed.

​Importantly, “epigenetics” is different from “genetics,” in which it is potentially reversible by dietary interventions and lifestyle changes.

Preliminary studies show that dietary changes can cause deceleration of the epigenetic clock in certain people. However, this is still an open question.

Lifestyle changes including exercise and change in dietary habits have been recommended by national medical associations for some time, however we need more data about the most advisable changes and they should be personalized.

One way for us to learn about advisable lifestyle changes is sharing our experiences with others and analyzing the impact of differences in lifestyle. This is now possible using sharing technologies such as Apps as well as artificial intelligence.

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Suppose the biological age is older than the actual age. In that case, These physical characteristics can happen as memory loss, insomnia, dreaminess, skin aging, collagen loss, gray hair, hair loss, fatigue, immune system decline, and other characteristics.

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Why Biological Age?

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Our Biological age is better parameter of our health, well-being, and life span than our chronological age. ​But how do we know our “biological age”?

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It has been believed that if we can define the true “biological age” we might test and design interventions that will decelerate the rate of biological aging. During the past decades, extensive effort has beed invested in identifying different parameters that could predict “biological aging” and life span such as measures of frailty, graying of hair, aging of skin, levels of different kinds of white blood cells. However most of these markers found to offer noadvantage over knowing your chronological age.

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How We Reveal Your Actual Age?

HKG epiTherapeutics is on the cutting edge of this “new age” science. It’s called Epigenetics and it uses a method called DNA methylation to determine your true age — which might, as science is thinking at this time and age, reveal some important information on your health, and possibly the quality and even span of your life. ​

Epigenetics is new, but already we have three decades of pioneering research in this exciting area of DNA methylation. With our  method of detecting the DNA methylation status stored in your cells, we might reveal your biological age which may encourage you to make  lifestyle changes.

What are the Parameters That Predict "Biological Aging" and Longevity?

• Measures of frailty

• Graying of hair

• Aging of skin

• Levels of different kinds of white blood cells

What Is The Epiaging Test? What Does It Mean?

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After extensive data mining, we have discovered a single age-related CG methylation region sufficient to accurately predict biological age using saliva.

Although it is still not clear how one can decelerate his age, lifestyle changes recommended by most national medical associations are perhaps a point to start.  Older age is a “red flag” that suggests perhaps it is time to make some lifestyle changes.

We consider a “red flag” an “epigenetic age” that is older than the standard deviation of the test. Standard deviation provides an idea about the distribution in the normal population, which at this point of the analysis is five years. As more tests are accumulated, we will get a more accurate number of the “normal distribution.”

A “red flag” might prompt you to act on your lifestyle.

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Why Does DNA Matter?

As the science of Epigenetics discovers exciting new approaches to determine your actual age, two important questions arise: what is  DNA, and why does it matter?

More than 99% of your  DNA is identical to everyone else’s. However, a small part of your DNA, which vary from person to person, makes you the unique person that you are.

More than traditional hair and eye color genetics, Epigenetics reveals a revolutionary understanding of your DNA and genetic code. These genetic “variants” can identify specific diseases you might be at risk for and enable you to change, fix or avoid them. Epigenetics holds the key to your overall health andwell-being.

These findings might lead to new treatments and drugs to prevent, treat or cure Cancer, Alzheimer's, Diabetes, Addiction, and others…perhaps before they occur.

HKG Epitherapeutics is the pioneer in developing advanced medical innovations for the earlydetection and prevention of diseases affect people worldwide. Our visions are already materialized.

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Why Do We Need Questionnaires In The App?

EpiAging tests make sense only within a dynamic life-long lifestyle, environmental and health management system.

A personalized evaluation including intervention will be generated based on the health and lifestyle information you provided.

Updates on your health and lifestyle parameters periodically to activate the life-long personalized analysis report.

How The Data Will Be Used?

Continuously analyze Epiaging test results, general health parameters, personal interventions and its outcomes of multiple users using state of the art machine learning algorithms.

Personalized analysis with some possible routes for improvement​.

Coevolving of your well being and our “Epiaging” learning environment.

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Telomere Length
Low correlation

High technical requirements Small technical errors may have a decisive ​impact on the results
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Etabolic age scores
Sampling and detection methods are complex and have not been verified in a large number of population samples
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Epigenetic Clock
Is closely related to the biological function of the human body, and the acceleration of the epigenetic clock was related to the risk of  certain diseases and cancer

The epigenetic age reflects the biological events that lead to aging. It is similar but not identical to the chronological age.

When it moves faster, it is an indication of faster aging, and when it moves slower, aging is slowed down.

Examining data from more than 3000 people, we calculated the average epigenetic clock for each age group.

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How does the Epiaging test work?

Our test is simple to administer, low cost, robust and accurate and is dynamically integrated into a life-long health ecosystem driven by App technology and machine learning.

Our App will link you to information on recommended lifestyle behaviors by major US national medical associations. These are updated regularly and we suggest that you keep updating by examining the links periodically. These recommendations are based on what “science” knows today, they are not perfect. With more data and more analysis science is improving.

You will update your lifestyle data as regularly as you wish. You might update all questions, some or none. However, we believe that accurate reporting will provide a more accurate and better analysis.

Initially, our report will show how far your lifestyle parameters are  from consensus recommendations. Your data will be anonymized and your data and data from other anonymous users we will be analyzed by machine learning, to develop a model based on many users that measures the impact, that lifestyle changes have on the “epigenetic clock”. In time, as more data is accumulated, the model will be used on your lifestyle data and will be shared withyou.

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Answer The Questions & Enter The Data

Discover Your Age

Make Lifestyle Changes, Improve Your Health

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